Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name cas
Flybase description The gene castor is referred to in FlyBase by the symbol Dmel\cas (CG2102, FBgn0004878).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -59.2817 -40.1588 -57.006318 -62.8624 -75.248651 -64.8392 -64.48079 -58.50905
    Affimetrix absolute value 2.529 2.303 2.359 2.427 2.55 2.545 2.554 2.41
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: DNA binding.
There is experimental evidence that it is involved in the biological process: central nervous system development; mushroom body development; post-embryonic development; neuroblast development; negative regulation of transcription, DNA-dependent.
31 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system subdivision; nervous system; multi-cell-component structure; synaptic neuropil subdomain; adult segment; sensillum; somatic cell; peripheral nervous system; organ system; sense organ.
It has one annotated transcript and one annotated polypeptide.
Protein features are: AT hook, DNA-binding motif; Zinc finger, C2H2; Zinc finger, C2H2-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.
Peak expression observed within 06-18 hour embryonic stages.
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