Flygut: an atlas of the Drosophila adult midgut

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Gene name tws
Flybase description The gene twins is referred to in FlyBase by the symbol Dmel\tws (CG6235, FBgn0004889).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.1913 -0.5662 -2.652412 -2.1168 -5.056241 -2.3084 5.89333 -2.488066
    Affimetrix absolute value 7.297 7.334 6.804 7.333 6.496 7.356 11.103 7.112
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein phosphatase type 2A regulator activity.
There is experimental evidence that it is involved in the biological process: negative regulation of neuroblast proliferation; maintenance of neuroblast polarity; mitotic cell cycle; mitotic anaphase; imaginal disc pattern formation; sensory organ development; embryonic development via the syncytial blastoderm; regulation of mitosis; Wnt receptor signaling pathway.
107 alleles are reported.
The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: sensillum; organ system; organ system subdivision; eo support cell; sense organ; cell cycle; adult segment; somatic cell; germarium; cellular component organization or biogenesis; somatic stem cell; chromosome, centromeric region; wing hair; dorsal thoracic disc; external compound sense organ.
It has 8 annotated transcripts and 8 annotated polypeptides.
Protein features are: Protein phosphatase 2A, regulatory subunit PR55; Protein phosphatase 2A, regulatory subunit PR55, conserved site; WD40 repeat; WD40 repeat, subgroup; WD40 repeat-like-containing domain; WD40/YVTN repeat-like-containing domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
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