Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Prat
Flybase description The gene Phosphoribosylamidotransferase is referred to in FlyBase by the symbol Dmel\Prat (CG2867, FBgn0004901).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.3552 -1.7915 -2.040878 -2.8527 -4.117572 -6.2112 -3.9673 -3.421408
    Affimetrix absolute value 6.665 6.782 7.149 6.878 6.729 5.957 6.589 6.479
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: amidophosphoribosyltransferase activity.
There is experimental evidence that it is involved in the biological process: determination of adult lifespan; embryonic cleavage; oogenesis.
12 alleles are reported.
The phenotypes of these alleles are annotated with: posterior crossvein; oocyte; follicle cell; border follicle cell; egg chamber.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Amidophosphoribosyl transferase; Glutamine amidotransferase, class-II; Glutamine amidotransferase, type II; Phosphoribosyltransferase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages, in adult female stages.
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