Flygut: an atlas of the Drosophila adult midgut

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Gene name Hnf4
Flybase description The gene Hepatocyte nuclear factor 4 is referred to in FlyBase by the symbol Dmel\Hnf4 (CG9310, FBgn0004914).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 0.4301 1.5885 -2.096933 -2.1942 -1.769011 -0.3565 -2.00133 -1.842518
    Affimetrix absolute value 8.534 8.267 7.132 7.264 7.971 8.529 7.573 7.464
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity; ligand-dependent nuclear receptor activity.
There is experimental evidence that it is involved in the biological process: lipid catabolic process; lipid oxidation.
24 alleles are reported.
No phenotypic data is available.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Nuclear hormone receptor, ligand-binding; Nuclear hormone receptor, ligand-binding, core; Retinoid X receptor; Steroid hormone receptor; Zinc finger, NHR/GATA-type; Zinc finger, nuclear hormone receptor-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 and 18-24 hour embryonic stages, in stages of adults of both sexes.
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