Flygut: an atlas of the Drosophila adult midgut

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Gene name M(2)21AB
Flybase description The gene S-adenosylmethionine Synthetase is referred to in FlyBase by the symbol Dmel\Sam-S (CG2674, FBgn0005278).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 2.7009 5.9224 2.0726 2.1157 -0.25349 2.1133 2.7232 2.009864
    Affimetrix absolute value 9.832 10.135 9.218 9.443 8.854 9.641 9.98 9.15
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: methionine adenosyltransferase activity.
There is experimental evidence that it is involved in the biological process: bristle development; wing disc development; S-adenosylmethionine biosynthetic process.
12 alleles are reported.
The phenotypes of these alleles are annotated with: eye; trichogen cell; macrochaeta; male genitalia; mesothoracic tergum; scutellar bristle; tergite.
It has 11 annotated transcripts and 11 annotated polypeptides.
Protein features are: S-adenosylmethionine synthetase; S-adenosylmethionine synthetase superfamily; S-adenosylmethionine synthetase, C-terminal; S-adenosylmethionine synthetase, N-terminal; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.
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