Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Su(fu)
Flybase description The gene Suppressor of fused is referred to in FlyBase by the symbol Dmel\Su(fu) (CG6054, FBgn0005355).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.8697 -3.2583 -6.857951 -6.4297 -10.385081 -8.3045 -3.98433 -7.941584
    Affimetrix absolute value 6.89 5.917 5.415 5.726 5.405 5.528 6.562 5.296
    Affymetric present call in "x" number of chips 3 3 3 3 3 2 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: transcription factor binding.
There is experimental evidence that it is involved in the biological process: negative regulation of sequence-specific DNA binding transcription factor activity; cytoplasmic sequestering of transcription factor; negative regulation of smoothened signaling pathway.
20 alleles are reported.
The phenotypes of these alleles are annotated with: sensillum campaniformium of dorsal radius; wing margin; wing disc; antenna; axillary vein; prothoracic leg; metathoracic leg; egg chamber; wing vein; costal vein.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Suppressor of fused domain; Suppressor of fused protein; Suppressor of fused-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages.
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