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Gene name | ewg | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene erect wing is referred to in FlyBase by the symbol Dmel\ewg (CG3114, FBgn0005427). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity; DNA binding. There is experimental evidence that it is involved in the biological process: negative regulation of synaptic growth at neuromuscular junction; central nervous system development; imaginal disc morphogenesis; muscle organ development. 77 alleles are reported. The phenotypes of these alleles are annotated with: dorsal medial muscle; NMJ bouton; embryonic/larval neuromuscular junction; mesothoracic tergum; wing; lateral oblique dorsal muscle. It has 10 annotated transcripts and 10 annotated polypeptides. Protein features are: Nuclear respiratory factor 1, NLS/DNA-binding, dimerisation domain; Nuclear respiratory factor-1, activation binding domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 06-18 hour embryonic stages. . |