Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Crc
Flybase description The gene Calreticulin is referred to in FlyBase by the symbol Dmel\Crc (CG9429, FBgn0005585).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 3.0794 10.0068 5.782612 6.1671 4.55605 5.9331 2.89169 5.489539
    Affimetrix absolute value 10.027 10.926 10.672 11.008 10.917 11.119 10.053 10.641
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: calcium ion binding.
There is experimental evidence that it is involved in the biological process: central nervous system development; startle response; brain morphogenesis; olfactory behavior; locomotion involved in locomotory behavior; neurogenesis.
39 alleles are reported.
The phenotypes of these alleles are annotated with: macrochaeta; presumptive embryonic/larval peripheral nervous system.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Calreticulin; Calreticulin/calnexin; Calreticulin/calnexin, conserved site; Concanavalin A-like lectin/glucanase; Concanavalin A-like lectin/glucanase, subgroup.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.
Peak expression observed within 06-18 hour embryonic stages.
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