Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name scw
Flybase description The gene screw is referred to in FlyBase by the symbol Dmel\scw (CG31695, FBgn0005590).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -51.6474 -33.2539 -44.309644 -48.5516 -63.125595 -57.6825 -56.54939 -44.524054
    Affimetrix absolute value 2.724 2.576 2.732 2.794 2.792 2.713 2.743 2.82
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein heterodimerization activity.
There is experimental evidence that it is involved in the biological process: digestive tract mesoderm development; gonad development.
35 alleles are reported.
The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: organ system; abdominal ventral denticle belt; organ system subdivision; spiracle; larval abdominal segment; primordium; adult segment; portion of tissue; extended germ band embryo; germ layer; integumentary specialisation.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Transforming growth factor beta, conserved site; Transforming growth factor-beta, C-terminal; Transforming growth factor-beta, N-terminal; Transforming growth factor-beta-related.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.
Peak expression observed within 00-06 hour embryonic stages.
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