Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Sox15
Flybase description The gene Sox box protein 15 is referred to in FlyBase by the symbol Dmel\Sox15 (CG8404, FBgn0005613).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -57.3514 -37.3185 -44.572697 -56.7109 -69.560292 -71.7505 -60.69813 -46.944776
    Affimetrix absolute value 2.586 2.419 2.724 2.563 2.641 2.408 2.638 2.717
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: bristle development; wing disc development; negative regulation of apoptosis; negative regulation of cell proliferation; negative regulation of transcription, DNA-dependent.
11 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; mechanosensory chaeta; wing sclerite; eo dendrite; wing blade; wing hinge primordium; tormogen cell; alula; joint; wing hinge.
It has one annotated transcript and one annotated polypeptide.
Protein features are: High mobility group, HMG1/HMG2; High mobility group, superfamily.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of extremely low expression.
Peak expression observed within 06-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages.
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