Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Hdc
Flybase description The gene Histidine decarboxylase is referred to in FlyBase by the symbol Dmel\Hdc (CG3454, FBgn0005619).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -71.745 -40.7807 -57.352166 -63.8438 -79.413375 -71.953 -73.16344 -68.316541
    Affimetrix absolute value 2.254 2.308 2.355 2.394 2.455 2.393 2.366 2.18
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: histidine decarboxylase activity.
There is experimental evidence that it is involved in the biological process: thermotaxis.
11 alleles are reported.
The phenotypes of these alleles are annotated with: lobula plate; retina.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Aromatic-L-amino-acid decarboxylase; Pyridoxal phosphate-dependent decarboxylase; Pyridoxal phosphate-dependent transferase, major domain; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; Pyridoxal phosphate-dependent transferase, major region, subdomain 2; Pyridoxal-phosphate binding site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.
Peak expression observed in adult male stages.
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