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Gene name | robo | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene roundabout is referred to in FlyBase by the symbol Dmel\robo (CG13521, FBgn0005631). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: heparin binding; protein binding. There is experimental evidence for 17 unique biological process terms, many of which group under: anatomical structure development; cellular component organization or biogenesis; biological regulation; locomotion; organ development; organ morphogenesis; regulation of biological process; neuromuscular process; taxis; dendrite morphogenesis. 53 alleles are reported. The phenotypes of these alleles are annotated with 52 unique terms, many of which group under: organ system subdivision; nervous system; embryonic/larval neuron; multi-cell-component structure; hypodermal muscle of larval abdomen; commissure; peripheral nervous system; presumptive embryonic/larval nervous system; A1-7 transverse muscle; sensillum; cell projection. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Fibronectin type III domain; Fibronectin, type III; Immunoglobulin I-set; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-18 hour embryonic stages, during early pupal stages. . |