Flygut: an atlas of the Drosophila adult midgut

 Mouche Logo lab lemaitre Bbcf logo
Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name spi
Flybase description The gene spitz is referred to in FlyBase by the symbol Dmel\spi (CG10334, FBgn0005672).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.559 0.4376 -1.766459 -1.5224 -2.270344 -1.6396 -2.54473 -1.910605
    Affimetrix absolute value 7.772 7.754 7.365 7.806 7.589 7.89 7.223 7.326
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: gurken receptor binding; epidermal growth factor receptor binding.
There is experimental evidence for 12 unique biological process terms, many of which group under: anatomical structure development; biological regulation; multicellular organismal process; positive regulation of cell proliferation; circulatory system process; cellular process involved in reproduction; response to chemical stimulus; regulation of biological process; post-embryonic appendage morphogenesis; heart process; stomatogastric nervous system development; determination of imaginal disc primordium; oenocyte development; open tracheal system development; regulation of apoptosis; behavioral response to ethanol.
84 alleles are reported.
The phenotypes of these alleles are annotated with 116 unique terms, many of which group under: organ system subdivision; external compound sense organ; organ system; nervous system; peripheral nervous system; abdominal lateral pentascolopidial chordotonal organ lch5; larval abdominal segment; hypodermal muscle of larval abdomen; adult segment; multi-cell-component structure.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: EGF; EGF-like region, conserved site; Epidermal growth factor-like; Epidermal growth factor-like, type 3.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages.
.