Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name dac
Flybase description The gene dachshund is referred to in FlyBase by the symbol Dmel\dac (CG4952, FBgn0005677).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -68.517 -35.6884 -41.037522 -55.5011 -62.250372 -77.2887 -70.30781 -51.469684
    Affimetrix absolute value 2.35 2.484 2.828 2.595 2.804 2.291 2.42 2.618
    Affymetric present call in "x" number of chips 0 0 0 0 1 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: axon guidance; compound eye photoreceptor development; compound eye development; neuron differentiation; mushroom body development; photoreceptor cell fate specification; antennal joint development; genital disc sexually dimorphic development.
65 alleles are reported.
The phenotypes of these alleles are annotated with 52 unique terms, many of which group under: organ system subdivision; adult segment; external compound sense organ; synaptic neuropil subdomain; peripheral nervous system; multi-cell-component structure; antennal segment; appendage segment; adult mesothoracic segment; imaginal precursor.
It has 7 annotated transcripts and 7 annotated polypeptides.
Protein features are: Bifunctional trypsin/alpha-amylase inhibitor; DNA binding domain, putative; Transforming protein Ski.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 06-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period.
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