Flygut: an atlas of the Drosophila adult midgut

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Gene name CanB
Flybase description The gene Calcineurin B is referred to in FlyBase by the symbol Dmel\CanB (CG4209, FBgn0010014).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -32.3035 -13.2491 -21.43086 -20.0958 -28.747351 -19.0504 -40.78334 -23.586202
    Affimetrix absolute value 3.401 3.943 3.774 4.106 3.933 4.318 3.203 3.733
    Affymetric present call in "x" number of chips 0 3 2 3 1 3 0 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: calcium ion binding; calcium-dependent protein serine/threonine phosphatase regulator activity; calmodulin binding.
There is experimental evidence that it is involved in the biological process: positive regulation of NFAT protein import into nucleus.
6 alleles are reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Calcium-binding EF-hand; EF-HAND 2; EF-Hand 1, calcium-binding site; EF-hand; EF-hand-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period.
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