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Gene name | CanB | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Calcineurin B is referred to in FlyBase by the symbol Dmel\CanB (CG4209, FBgn0010014). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: calcium ion binding; calcium-dependent protein serine/threonine phosphatase regulator activity; calmodulin binding. There is experimental evidence that it is involved in the biological process: positive regulation of NFAT protein import into nucleus. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Calcium-binding EF-hand; EF-HAND 2; EF-Hand 1, calcium-binding site; EF-hand; EF-hand-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period. . |