Flygut: an atlas of the Drosophila adult midgut

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Gene name Itp-r83A
Flybase description The gene Inositol 1,4,5,-tris-phosphate receptor is referred to in FlyBase by the symbol Dmel\Itp-r83A (CG1063, FBgn0010051).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -5.7 -2.8044 -9.691101 -4.6968 -22.961382 -11.5641 -3.16189 -13.818741
    Affimetrix absolute value 5.91 6.145 4.939 6.194 4.357 5.033 6.936 4.576
    Affymetric present call in "x" number of chips 3 3 1 3 1 3 3 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity.
There is experimental evidence that it is involved in the biological process: larval feeding behavior; cellular calcium ion homeostasis; stabilization of membrane potential; response to oxidative stress; nuclear division; flight behavior; molting cycle, chitin-based cuticle; mushroom body development; release of sequestered calcium ion into cytosol; sensory perception of taste.
42 alleles are reported.
The phenotypes of these alleles are annotated with: dorsal medial muscle; mushroom body; wing margin; mesothoracic tergum; wing; antennal lobe; indirect flight muscle.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Inositol 1,4,5-trisphosphate-binding protein receptor; Inositol 1,4,5-trisphosphate/ryanodine receptor; Intracellular calcium-release channel; Ion transport; MIR; MIR motif; RyR/IP3R Homology associated domain; Ryanodine receptor-related.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 12-18 embryonic stages.
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