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Gene name | Acon | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Aconitase is referred to in FlyBase by the symbol Dmel\Acon (CG9244, FBgn0010100). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: aconitate hydratase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: tricarboxylic acid cycle. 21 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Aconitase A/isopropylmalate dehydratase small subunit, swivel; Aconitase family, 4Fe-4S cluster binding site; Aconitase, mitochondrial-like; Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3; Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2; Aconitase/3-isopropylmalate dehydratase, swivel; Aconitase/isopropylmalate dehydratase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes. . |