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Gene name | comm | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene commissureless is referred to in FlyBase by the symbol Dmel\comm (CG17943, FBgn0010105). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: WW domain binding; protein binding. There is experimental evidence that it is involved in the biological process: synapse assembly; receptor internalization; positive regulation of receptor internalization; axon guidance; dendrite morphogenesis; axon midline choice point recognition; neuron recognition; dendrite guidance. 72 alleles are reported. The phenotypes of these alleles are annotated with 30 unique terms, many of which group under: organ system subdivision; embryonic/larval neuron; commissure; multi-cell-component structure; nervous system; peripheral nervous system; presumptive embryonic/larval nervous system; thoracic segment; embryonic/larval tracheal system; synaptic neuropil subdomain; cell projection; ganglionic branch primordium; antennal segment. It has one annotated transcript and one annotated polypeptide. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 00-12 hour embryonic stages. . |