Flygut: an atlas of the Drosophila adult midgut

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Gene name Myo61F
Flybase description The gene Myosin 61F is referred to in FlyBase by the symbol Dmel\Myo61F (CG9155, FBgn0010246).
Expression data along the gut
    Created with Highcharts 6.0.3Fold change compared to full gutRegion-specific expression of Myo61F along the gutCropCardia/R1R2R3R4R5Hindgut-100-75-50-25025Highcharts.com
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -8.1317 11.6224 16.629549 5.9469 10.503158 13.648 0.7751 12.115889
    Affimetrix absolute value 5.414 11.153 12.218 10.943 12.142 12.328 8.993 11.766
    Affymetric present call in "x" number of chips 0 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Created with Highcharts 6.0.3Fold change compared toUnchallengedFold change compared to UnchallengedExpression of Myo61F in different experimental conditionsEcc15 4hEcc15 16hPe 4hPe 16hPe gacA 4hPe gacA 16h-2-1012Highcharts.com
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: ATPase activity, coupled.
There is experimental evidence that it is involved in the biological process: determination of left/right symmetry; defense response to bacterium; microvillus organization; mesoderm development.
12 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic/larval midgut; embryonic hindgut; enterocyte; embryonic/larval midgut primordium; microvillus; brush border.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: IQ motif, EF-hand binding site; Myosin head, motor domain; Myosin tail 2.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression.
Peak expression observed within 18-24 hour embryonic stages.
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