Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name TfIIFalpha
Flybase description The gene Transcription factor IIFα is referred to in FlyBase by the symbol Dmel\TfIIFα (CG10281, FBgn0010282).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -4.4068 -1.7234 -2.584307 -2.8792 -4.588082 -4.0507 -3.84836 -3.504994
    Affimetrix absolute value 6.276 6.854 6.837 6.867 6.578 6.561 6.647 6.486
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: catalytic activity; DNA binding.
There is experimental evidence that it is involved in the biological process: neurogenesis.
4 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Transcription Factor IIF, Rap30/Rap74, interaction; Transcription initiation factor IIF, alpha subunit; Winged helix-turn-helix transcription repressor DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.
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