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Gene name | brat | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene brain tumor is referred to in FlyBase by the symbol Dmel\brat (CG10719, FBgn0010300). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; translation repressor activity. There is experimental evidence for 16 unique biological process terms, many of which group under: anatomical structure development; biological regulation; cellular component organization or biogenesis; cell division; cellular macromolecule metabolic process; cell fate commitment; cell fate determination; ncRNA metabolic process; neuroblast fate commitment; multicellular organismal reproductive process; gene expression; multicellular organismal process. 105 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system; organ system subdivision; germarium; female germline cyst; multicellular structure; nervous system; somatic cell; embryonic abdomen; embryonic segment; imaginal precursor; external compound sense organ; adult segment. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: NHL repeat; NHL repeat, subgroup; Six-bladed beta-propeller, TolB-like; Zinc finger, B-box. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. . |