Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name hep
Flybase description The gene hemipterous is referred to in FlyBase by the symbol Dmel\hep (CG4353, FBgn0010303).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -29.9015 -13.7257 -21.590639 -23.1738 -37.527821 -25.3263 -27.40078 -28.331616
    Affimetrix absolute value 3.51 3.846 3.777 3.875 3.554 3.914 3.82 3.481
    Affymetric present call in "x" number of chips 0 1 0 1 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; protein kinase activity.
There is experimental evidence for 26 unique biological process terms, many of which group under: anatomical structure development; cellular component organization or biogenesis; biological regulation; cellular process involved in reproduction; multicellular organismal reproductive process; cellular response to inorganic substance; chemical homeostasis; post-embryonic organ morphogenesis; response to stress; response to chemical stimulus.
46 alleles are reported.
The phenotypes of these alleles are annotated with 38 unique terms, many of which group under: organ system subdivision; adult segment; organ system; imaginal precursor; external compound sense organ; adult mesothoracic segment; thoracic segment; non-connected developing system; nervous system; larval thorax.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, in adult female stages.
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