Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Rac1
Flybase description The gene Rac1 is referred to in FlyBase by the symbol Dmel\Rac1 (CG2248, FBgn0010333).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.4194 1.673 1.307131 1.3284 -1.405657 1.1273 -0.40885 0.241309
    Affimetrix absolute value 7.926 8.343 8.553 8.788 8.275 8.731 8.451 8.159
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: GTPase activity.
There is experimental evidence for 41 unique biological process terms, many of which group under: anatomical structure development; cellular component organization or biogenesis; biological regulation; localization; regulation of multicellular organismal development; actin filament-based process; cell proliferation; cellular process involved in reproduction; open tracheal system development; muscle cell differentiation.
46 alleles are reported.
The phenotypes of these alleles are annotated with 87 unique terms, many of which group under: organ system subdivision; adult segment; multi-cell-component structure; embryonic/larval neuron; primordium; peripheral nervous system; hemocyte; female germline cyst; cell projection; late extended germ band embryo.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Small GTP-binding protein domain; Small GTPase superfamily; Small GTPase superfamily, Rho type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages.
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