Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Dbi
Flybase description The gene Diazepam-binding inhibitor is referred to in FlyBase by the symbol Dmel\Dbi (CG8627, FBgn0010387).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 44.7578 49.2835 26.865007 3.9662 23.563815 19.466 3.66262 27.849552
    Affimetrix absolute value 13.874 13.215 12.898 10.355 13.298 12.842 10.38 13.008
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: diazepam binding; enzyme inhibitor activity; fatty-acyl-CoA binding.
Based on sequence similarity, it is predicted to be involved in the biological process: cellular acyl-CoA homeostasis.
One allele is reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Acyl-CoA-binding protein, ACBP; Acyl-CoA-binding protein, ACBP, conserved site; FERM/acyl-CoA-binding protein, 3-helical bundle.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression.
Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.
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