Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name ato
Flybase description The gene atonal is referred to in FlyBase by the symbol Dmel\ato (CG7508, FBgn0010433).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -17.4464 -12.1309 -14.741119 -17.8214 -25.142356 -19.8137 -14.8459 -19.867072
    Affimetrix absolute value 4.284 4.053 4.304 4.233 4.15 4.276 4.664 4.013
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: DNA binding; sequence-specific DNA binding transcription factor activity.
There is experimental evidence for 17 unique biological process terms, many of which group under: anatomical structure development; organ morphogenesis; post-embryonic organ morphogenesis; sensory organ development; organ development; biological regulation; regulation of biological process; neuron differentiation; signaling; cellular component organization or biogenesis; multicellular organismal reproductive process; sensory perception of mechanical stimulus.
30 alleles are reported.
The phenotypes of these alleles are annotated with 58 unique terms, many of which group under: organ system subdivision; adult segment; antennal segment; external compound sense organ; abdominal lateral pentascolopidial chordotonal organ lch5; nervous system; multi-cell-component structure; imaginal precursor; late extended germ band embryo; adult mesothoracic segment.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Helix-loop-helix DNA-binding; Helix-loop-helix DNA-binding domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.
Peak expression observed within 06-12 hour embryonic stages.
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