Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name cora
Flybase description The gene coracle is referred to in FlyBase by the symbol Dmel\cora (CG11949, FBgn0010434).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.448 -1.1479 -2.328547 -0.3204 -3.72522 -0.7071 -2.10939 -2.677002
    Affimetrix absolute value 7.135 7.426 7.076 8.39 6.967 8.149 7.542 6.93
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: cytoskeletal protein binding.
There is experimental evidence that it is involved in the biological process: adult somatic muscle development; embryonic morphogenesis; maintenance of imaginal disc-derived wing hair orientation; regulation of tube size, open tracheal system; establishment of glial blood-brain barrier.
44 alleles are reported.
The phenotypes of these alleles are annotated with 19 unique terms, many of which group under: organ system subdivision; external compound sense organ; organ system; non-connected developing system; integumentary plate; plasma membrane part; adult segment; compound cell cluster organ; sensillum; plasma membrane.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Band 4.
1 domain; Band 4.
1 family; Band 4.
1, C-terminal; FERM adjacent (FA); FERM central domain; FERM conserved site; FERM domain; FERM, C-terminal PH-like domain; FERM, N-terminal; FERM/acyl-CoA-binding protein, 3-helical bundle; Pleckstrin homology-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed within 12-24 hour embryonic stages.
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