Flygut: an atlas of the Drosophila adult midgut

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Gene name Dcp-1
Flybase description The gene Death caspase-1 is referred to in FlyBase by the symbol Dmel\Dcp-1 (CG5370, FBgn0010501).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -33.4248 -11.5222 -1.581579 -1.1988 -2.489799 -1.7264 -15.92793 -2.639279
    Affimetrix absolute value 3.371 4.101 7.547 8.136 7.471 7.775 4.631 6.939
    Affymetric present call in "x" number of chips 1 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: cysteine-type endopeptidase activity.
There is experimental evidence that it is involved in the biological process: apoptosis; ovarian nurse cell to oocyte transport; cleavage of lamin; actin cytoskeleton organization; programmed cell death; neuron remodeling; embryo development; autophagic cell death; developmental programmed cell death; salivary gland cell autophagic cell death.
39 alleles are reported.
The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system; imaginal precursor; external compound sense organ; organ system subdivision; nervous system; embryonic/larval imaginal precursor; female germline cyst; cell projection; neuron projection; pigment cell; cell part; tracheal system; peripheral nervous system.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Peptidase C14, ICE, catalytic subunit p20; Peptidase C14, ICE, catalytic subunit p20, active site; Peptidase C14, caspase catalytic; Peptidase C14, caspase non-catalytic subunit p10; Peptidase C14, caspase precursor p45; Peptidase C14, caspase precursor p45, core.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.
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