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Gene name | dock | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene dreadlocks is referred to in FlyBase by the symbol Dmel\dock (CG3727, FBgn0010583). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: insulin receptor binding. There is experimental evidence that it is involved in the biological process: insulin receptor signaling pathway; axon guidance. 34 alleles are reported. The phenotypes of these alleles are annotated with 27 unique terms, many of which group under: organ system subdivision; multi-cell-component structure; external compound sense organ; peripheral nervous system; synaptic neuropil subdomain; embryonic/larval neuron; nervous system; adult segment; antennal segment; lobula complex; lamina neuropil; commissure. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Cytoplasmic, NCK; Neutrophil cytosol factor 2 p67phox; SH2 motif; Src homology-3 domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages. . |