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Gene name | Hmgs | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene HMG Coenzyme A synthase is referred to in FlyBase by the symbol Dmel\Hmgs (CG4311, FBgn0010611). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: hydroxymethylglutaryl-CoA synthase activity. There is experimental evidence that it is involved in the biological process: lateral inhibition; embryonic development via the syncytial blastoderm; neurogenesis. 9 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Hydroxymethylglutaryl-CoA synthase, eukaryotic; Hydroxymethylglutaryl-coenzyme A synthase C-terminal; Hydroxymethylglutaryl-coenzyme A synthase, N-terminal; Hydroxymethylglutaryl-coenzyme A synthase, active site; Thiolase-like; Thiolase-like, subgroup. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 12-18 embryonic stages, during early larval stages. . |