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Gene name | Sec61beta | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Sec61β is referred to in FlyBase by the symbol Dmel\Sec61β (CG10130, FBgn0010638). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: protein transporter activity. There is experimental evidence that it is involved in the biological process: negative regulation of autophagy. 16 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; leg; chorion; embryonic/larval trachea; egg; dorsal appendage; denticle belt. It has one annotated transcript and one annotated polypeptide. Protein features are: Preprotein translocase Sec, Sec61-beta subunit; Preprotein translocase Sec, Sec61-beta subunit, eukarya. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages. . |