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| Gene name | l(3)02640 | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene lethal (3) 02640 is referred to in FlyBase by the symbol Dmel\l(3)02640 (CG9165, FBgn0010786). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: hydroxymethylbilane synthase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: peptidyl-pyrromethane cofactor linkage; tetrapyrrole biosynthetic process. 19 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Porphobilinogen deaminase, C-terminal domain; Porphobilinogen deaminase, N-terminal; Porphobilinogen deaminase, dipyrromethane cofactor binding site; Tetrapyrrole biosynthesis, hydroxymethylbilane synthase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 and 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes. . |
