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Gene name | Gug | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Grunge is referred to in FlyBase by the symbol Dmel\Gug (CG6964, FBgn0010825). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: histone deacetylase activity; repressing transcription factor binding; transcription corepressor activity; DNA binding. There is experimental evidence that it is involved in the biological process: eye development; segment specification; negative regulation of epidermal growth factor receptor signaling pathway; embryonic pattern specification; segmentation; imaginal disc-derived wing vein morphogenesis; imaginal disc-derived leg morphogenesis; negative regulation of transcription, DNA-dependent. 43 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system subdivision; adult segment; external compound sense organ; organ system; cytoplasmic part; adult mesothoracic segment; thoracic segment; nervous system; compound cell cluster organ; organelle. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: Atrophin-like; ELM2 domain; Homeodomain-like; SANT domain, DNA binding; SANT, eukarya. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. . |