Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name sinu
Flybase description The gene sinuous is referred to in FlyBase by the symbol Dmel\sinu (CG10624, FBgn0010894).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 0.6362 -1.2565 -4.836963 -3.1666 -7.888624 -4.2318 2.42338 -3.10964
    Affimetrix absolute value 8.754 7.298 5.929 6.727 5.822 6.485 9.809 6.66
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: regulation of tube size, open tracheal system; establishment of glial blood-brain barrier; open tracheal system development; septate junction assembly.
10 alleles are reported.
The phenotypes of these alleles are annotated with: taenidial fold; trichogen cell; embryonic/larval dorsal trunk; septate junction; heart primordium; presumptive embryonic/larval tracheal system; embryonic/larval tracheal system; dorsal trunk primordium; embryonic/larval transverse connective.
It has 2 annotated transcripts and 2 annotated polypeptides.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 06-18 hour embryonic stages.
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