Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name dia
Flybase description The gene diaphanous is referred to in FlyBase by the symbol Dmel\dia (CG1768, FBgn0011202).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 0.3687 2.4063 1.54178 1.6269 -1.526748 1.4417 2.67346 0.417113
    Affimetrix absolute value 8.458 8.858 8.755 9.074 8.175 9.089 9.955 8.352
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence for 19 unique biological process terms, many of which group under: cell cycle; anatomical structure development; cellular component organization or biogenesis; multicellular organismal process; cell division; localization; biological regulation; cell cycle process; multicellular organismal reproductive process; cellular process involved in reproduction; apical constriction; embryonic development via the syncytial blastoderm; sensory perception of mechanical stimulus.
26 alleles are reported.
The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: organ system; organ system subdivision; female germline cyst; portion of tissue; somatic cell; non-connected developing system; multi-cell-component structure; presumptive embryonic/larval nervous system; spermatocyte; cytoplasmic part; imaginal precursor; external compound sense organ; commissure; late extended germ band embryo.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Actin-binding FH2; Actin-binding FH2/DRF autoregulatory; Armadillo-type fold; DRF autoregulatory; Diaphanous FH3; Diaphanous GTPase-binding; Diaphanous autoregulatory; GTPase-binding/formin homology 3.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-12 and 18-24 hour embryonic stages, during late larval stages, during early pupal stages.
.