Flygut: an atlas of the Drosophila adult midgut

 Mouche Logo lab lemaitre Bbcf logo
Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name fbl
Flybase description The gene fumble is referred to in FlyBase by the symbol Dmel\fbl (CG5725, FBgn0011205).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 3.3529 2.8812 2.408151 0.4056 1.446488 1.8719 -0.6381 1.742303
    Affimetrix absolute value 10.094 9.134 9.431 8.482 9.275 9.464 8.195 8.974
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: pantothenate kinase activity.
There is experimental evidence that it is involved in the biological process: triglyceride homeostasis; locomotion; meiosis; chromosome segregation; mitosis; cellular membrane organization; cytokinesis; oogenesis; imaginal disc-derived wing morphogenesis; spermatogenesis.
17 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; organ system subdivision; adult segment; cell cycle; adult mesothoracic segment; nervous system; cellular component organization or biogenesis; elongation stage spermatid; cytoplasmic part; male germline cyst.
It has 7 annotated transcripts and 7 annotated polypeptides.
Protein features are: Type II pantothenate kinase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes.
.