Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name blw
Flybase description The gene bellwether is referred to in FlyBase by the symbol Dmel\blw (CG3612, FBgn0011211).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 0.3315 -6.232 -9.485856 -10.9448 -13.30242 -10.2893 -3.35726 -6.957772
    Affimetrix absolute value 8.407 5.016 4.932 4.936 5.048 5.2 6.811 5.462
    Affymetric present call in "x" number of chips 3 3 1 2 1 1 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: hydrogen-exporting ATPase activity, phosphorylative mechanism.
There is experimental evidence that it is involved in the biological process: growth; spermatid development; phagocytosis, engulfment.
31 alleles are reported.
The phenotype of these alleles is annotated with: mesothoracic tergum.
It has one annotated transcript and one annotated polypeptide.
Protein features are: ATPase, F1 complex, alpha subunit; ATPase, F1/A1 complex, alpha subunit, N-terminal; ATPase, F1/A1 complex, alpha/beta subunit, N-terminal; ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal; ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; ATPase, alpha/beta subunit, nucleotide-binding domain, active site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.
Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.
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