Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name eff
Flybase description The gene effete is referred to in FlyBase by the symbol Dmel\eff (CG7425, FBgn0011217).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 3.7378 6.9283 5.552341 5.9112 3.769451 4.6825 3.99039 4.773296
    Affimetrix absolute value 10.284 10.406 10.648 10.946 10.672 10.784 10.54 10.459
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; ubiquitin-protein ligase activity.
There is experimental evidence for 15 unique biological process terms, many of which group under: anatomical structure development; biological regulation; cellular component organization or biogenesis; cellular process involved in reproduction; catabolic process; cellular macromolecule metabolic process; cell cycle; sensory organ development; macromolecule modification; neuron maturation; cell cycle process; regulation of developmental process; multicellular organismal reproductive process; organ morphogenesis.
70 alleles are reported.
The phenotypes of these alleles are annotated with: nurse cell fusome; neuron; dendrite; macrochaeta; mesothoracic leg; testis; dorsal multidendritic neuron ddaC; nuclear chromosome; female germline stem cell; germarium.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Ubiquitin-conjugating enzyme, E2; Ubiquitin-conjugating enzyme, active site; Ubiquitin-conjugating enzyme/RWD-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
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