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Gene name | heph | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene hephaestus is referred to in FlyBase by the symbol Dmel\heph (CG31000, FBgn0011224). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: mRNA 3'-UTR binding; translation repressor activity, nucleic acid binding. There is experimental evidence that it is involved in the biological process: spermatid development; imaginal disc-derived wing margin morphogenesis; sperm individualization; oocyte microtubule cytoskeleton polarization; imaginal disc-derived wing vein morphogenesis; Notch signaling pathway; negative regulation of oskar mRNA translation. 113 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; elongation stage spermatid; macrochaeta; testis; mesothoracic tergum; wing; spermatid cyst; individualization stage spermatid; spermatozoon. It has 24 annotated transcripts and 24 annotated polypeptides. Protein features are: HnRNP-L/PTB/hephaestus splicing factor; Nucleotide-binding, alpha-beta plait; RNA recognition motif domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during early pupal stages. . |