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Gene name | ken | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene ken and barbie is referred to in FlyBase by the symbol Dmel\ken (CG5575, FBgn0011236). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity; nucleic acid binding. There is experimental evidence that it is involved in the biological process: imaginal disc-derived female genitalia development; female analia development; male analia development; insemination; imaginal disc-derived male genitalia development; regulation of JAK-STAT cascade; phagocytosis, engulfment. 29 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system subdivision; organ system; region of integument; adult segment; adult; antennal segment; larval abdominal segment; spiracle; vagina; late extended germ band embryo. It has one annotated transcript and one annotated polypeptide. Protein features are: BTB/POZ; BTB/POZ fold; BTB/POZ-like; Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, C2H2-type/integrase, DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 12-18 embryonic stages. . |