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Gene name | Sema-1a | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Sema-1a is referred to in FlyBase by the symbol Dmel\Sema-1a (CG18405, FBgn0011259). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: synapse assembly; synaptic target recognition; startle response; brain morphogenesis; axon guidance; dendrite morphogenesis; semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance; locomotion involved in locomotory behavior; axon midline choice point recognition. 32 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system subdivision; multi-cell-component structure; presumptive embryonic/larval nervous system; commissure; peripheral nervous system; nervous system; synapse; abdominal segmental nerve; adult segment; presumptive embryonic/larval central nervous system. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Plexin; Plexin-like fold; Plexin/semaphorin/integrin; Semaphorin/CD100 antigen; WD40/YVTN repeat-like-containing domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 12-18 embryonic stages. . |