Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Sema-2a
Flybase description The gene Sema-2a is referred to in FlyBase by the symbol Dmel\Sema-2a (CG4700, FBgn0011260).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -5.6327 -2.0722 -3.300771 -2.8816 -4.01266 -1.3787 -12.37063 -3.421766
    Affimetrix absolute value 5.951 6.577 6.504 6.87 6.813 8.107 4.979 6.543
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: adult behavior; axon guidance; visual behavior; flight behavior; synaptic target inhibition; salivary gland development; drinking behavior.
19 alleles are reported.
The phenotypes of these alleles are annotated with: abdominal 1 RP3 neuron; abdominal 2 RP1 neuron; RP3 neuron; intersegmental nerve; abdominal 2 RP3 neuron; abdominal segmental nerve; imaginal disc; abdominal 1 RP1 neuron; transverse nerve; synapse.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Immunoglobulin subtype; Immunoglobulin-like; Immunoglobulin-like fold; Plexin-like fold; Plexin/semaphorin/integrin; Semaphorin/CD100 antigen; WD40/YVTN repeat-like-containing domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed within 00-18 hour embryonic stages.
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