Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name HLH3B
Flybase description The gene Helix loop helix protein 3B is referred to in FlyBase by the symbol Dmel\HLH3B (CG2655, FBgn0011276).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -29.997 -17.1659 -23.398769 -30.7054 -34.976418 -34.9849 -27.49685 -27.162368
    Affimetrix absolute value 3.519 3.533 3.664 3.457 3.663 3.441 3.775 3.534
    Affymetric present call in "x" number of chips 0 0 0 0 1 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
The biological processes in which it is involved are not known.
4 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Helix-loop-helix DNA-binding; Helix-loop-helix DNA-binding domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 06-12 hour embryonic stages.
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