Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name lbe
Flybase description The gene ladybird early is referred to in FlyBase by the symbol Dmel\lbe (CG6545, FBgn0011278).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -32.4221 -17.3007 -28.177299 -29.2018 -39.15976 -35.3728 -29.04879 -26.957164
    Affimetrix absolute value 3.396 3.547 3.408 3.521 3.473 3.42 3.694 3.522
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence for 13 unique biological process terms, many of which group under: anatomical structure development; biological regulation; organ development; muscle organ development; regulation of developmental process; cellular component organization or biogenesis; localization; myoblast proliferation; regulation of cellular macromolecule biosynthetic process; cell proliferation; leg morphogenesis; locomotion; post-embryonic organ morphogenesis; muscle cell differentiation; regulation of multicellular organismal development.
7 alleles are reported.
The phenotypes of these alleles are annotated with 27 unique terms, many of which group under: adult abdominal myoblast; organ system; adult; organ system subdivision; hypodermal muscle of larval abdomen; myoblast; abdominal segment 7; multi-cell-component structure; embryonic/larval hypodermal muscle; adult somatic muscle; embryonic/larval neuron; primordium.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Helix-turn-helix motif, lambda-like repressor; Homeobox; Homeobox, conserved site; Homeobox, eukaryotic; Homeodomain-like; Homeodomain-related.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very low expression to a trough of no expression detected.
Peak expression observed within 06-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages.
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