Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name babo
Flybase description The gene baboon is referred to in FlyBase by the symbol Dmel\babo (CG8224, FBgn0011300).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -10.666 -2.099 -2.755273 -2.8391 -5.979462 -3.5073 -3.88686 -5.886848
    Affimetrix absolute value 5.02 6.563 6.768 6.912 6.249 6.759 6.618 5.908
    Affymetric present call in "x" number of chips 1 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: activin binding.
There is experimental evidence that it is involved in the biological process: activin receptor signaling pathway; axon guidance; neuron development; eye-antennal disc morphogenesis; regulation of mitotic cell cycle; neuroblast proliferation; imaginal disc-derived wing morphogenesis; mushroom body development; response to UV.
37 alleles are reported.
The phenotypes of these alleles are annotated with 30 unique terms, many of which group under: organ system subdivision; multi-cell-component structure; adult segment; nervous system; spiracle; external compound sense organ; presumptive embryonic/larval nervous system; adult mesothoracic segment; imaginal precursor; synaptic neuropil subdomain; dorsal thoracic disc.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain; TGF beta receptor, GS motif; TGF-beta receptor/activin receptor, type I/II.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.
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