Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name l(3)neo18
Flybase description The gene lethal (3) neo18 is referred to in FlyBase by the symbol Dmel\l(3)neo18 (CG9762, FBgn0011455).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 8.1108 7.3335 5.059763 7.7498 3.3242 5.2878 10.40188 5.163879
    Affimetrix absolute value 11.416 10.469 10.465 11.336 10.453 10.958 11.919 10.495
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity.
There is experimental evidence that it is involved in the biological process: determination of adult lifespan; response to reactive oxygen species.
4 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression.
Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in stages of adults of both sexes.
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