Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name pr-set7
Flybase description The gene pr-set7 is referred to in FlyBase by the symbol Dmel\pr-set7 (CG3307, FBgn0011474).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -17.0726 -6.9403 -13.585605 -11.2183 -23.874224 -11.2262 -7.94306 -18.748734
    Affimetrix absolute value 4.316 4.833 4.451 4.921 4.209 5.082 5.597 4.024
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: histone methyltransferase activity (H4-K20 specific).
There is experimental evidence that it is involved in the biological process: histone methylation; chromosome condensation; histone H4-K20 monomethylation; DNA damage checkpoint.
6 alleles are reported.
The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; organ system subdivision; thoracic segment; multicellular structure; adult segment; larval thorax; adult mesothoracic segment; imaginal precursor; embryonic/larval tracheal system; organelle; sensillum; dorsal thoracic disc; external compound sense organ.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: SET domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages.
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