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Gene name | cpb | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene capping protein beta is referred to in FlyBase by the symbol Dmel\cpb (CG17158, FBgn0011570). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: actin binding. There is experimental evidence that it is involved in the biological process: wing disc development; regulation of lamellipodium assembly; border follicle cell migration; actin cytoskeleton organization; regulation of actin filament length; barbed-end actin filament capping; cytoplasmic transport, nurse cell to oocyte; actin filament organization; negative regulation of filopodium assembly. 15 alleles are reported. The phenotypes of these alleles are annotated with: sternopleural bristle; macrochaeta; border follicle cell; nurse cell. It has one annotated transcript and one annotated polypeptide. Protein features are: F-actin capping protein, beta subunit, conserved site; WASH complex, F-actin capping protein, beta subunit. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages. . |