Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name cpb
Flybase description The gene capping protein beta is referred to in FlyBase by the symbol Dmel\cpb (CG17158, FBgn0011570).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 0.535 2.3223 1.632633 3.5123 -0.256313 2.2919 1.22434 0.88392
    Affimetrix absolute value 8.656 8.828 8.822 10.195 8.839 9.757 8.826 8.81
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: actin binding.
There is experimental evidence that it is involved in the biological process: wing disc development; regulation of lamellipodium assembly; border follicle cell migration; actin cytoskeleton organization; regulation of actin filament length; barbed-end actin filament capping; cytoplasmic transport, nurse cell to oocyte; actin filament organization; negative regulation of filopodium assembly.
15 alleles are reported.
The phenotypes of these alleles are annotated with: sternopleural bristle; macrochaeta; border follicle cell; nurse cell.
It has one annotated transcript and one annotated polypeptide.
Protein features are: F-actin capping protein, beta subunit, conserved site; WASH complex, F-actin capping protein, beta subunit.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression.
Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.
.