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Gene name | La | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene La autoantigen-like is referred to in FlyBase by the symbol Dmel\La (CG10922, FBgn0011638). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: 5S rRNA primary transcript binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: RNA processing. 4 alleles are reported. The phenotypes of these alleles are annotated with: midgut constriction 2; trichogen cell; midgut constriction; midgut constriction 1; midgut constriction 3. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Lupus La protein; Nucleotide-binding, alpha-beta plait; RNA recognition motif domain; RNA-binding motif; RNA-binding protein Lupus La; Winged helix-turn-helix transcription repressor DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 06-12 hour embryonic stages, during early larval stages, in adult female stages. . |