Flygut: an atlas of the Drosophila adult midgut

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Gene name La
Flybase description The gene La autoantigen-like is referred to in FlyBase by the symbol Dmel\La (CG10922, FBgn0011638).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.8724 -1.3591 -1.587889 -1.7267 -2.091358 -2.1562 -2.92577 -1.957741
    Affimetrix absolute value 7.513 7.191 7.512 7.607 7.714 7.481 7.033 7.286
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: 5S rRNA primary transcript binding.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: RNA processing.
4 alleles are reported.
The phenotypes of these alleles are annotated with: midgut constriction 2; trichogen cell; midgut constriction; midgut constriction 1; midgut constriction 3.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Lupus La protein; Nucleotide-binding, alpha-beta plait; RNA recognition motif domain; RNA-binding motif; RNA-binding protein Lupus La; Winged helix-turn-helix transcription repressor DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 06-12 hour embryonic stages, during early larval stages, in adult female stages.
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