Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Mef2
Flybase description The gene Myocyte enhancer factor 2 is referred to in FlyBase by the symbol Dmel\Mef2 (CG1429, FBgn0011656).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 2.8471 8.7763 4.841955 -0.3033 -1.093959 -0.1334 4.75732 2.227352
    Affimetrix absolute value 9.914 10.678 10.297 8.423 8.093 8.736 10.705 9.374
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: myoblast fusion; muscle fiber development; skeletal muscle tissue development; regulation of gene expression; anterior midgut development; locomotor rhythm; mesoderm development.
64 alleles are reported.
The phenotypes of these alleles are annotated with 47 unique terms, many of which group under: organ system; adult segment; organ system subdivision; hypodermal muscle of larval abdomen; adult mesothoracic segment; A1-7 transverse muscle; non-connected developing system; primordium; eo support cell; egg.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: Holliday junction regulator protein family C-terminal repeat; Transcription factor, MADS-box.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 06-12 hour embryonic stages.
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