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| Gene name | Mlh1 | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene Mlh1 is referred to in FlyBase by the symbol Dmel\Mlh1 (CG11482, FBgn0011659). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: mismatched DNA binding; ATP binding. Based on sequence similarity, it is predicted to be involved in the biological process: mismatch repair. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: ATPase-like, ATP-binding domain; DNA mismatch repair protein; DNA mismatch repair protein Mlh1; DNA mismatch repair protein, C-terminal; DNA mismatch repair protein, N-terminal; DNA mismatch repair, conserved site; Ribosomal protein S5 domain 2-type fold; Ribosomal protein S5 domain 2-type fold, subgroup. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 00-12 hour embryonic stages, during early pupal stages, in adult female stages. . |
